.BETA.-Glucuronidase-Inhibitory Activity and Hepatoprotective Effect of Ganoderma lucidum.

Anticancer and Antibacterial Activity of Ganoderma lucidum

ISSN: 2319-7706 Volume 5 Number 10 (2016) pp. 891-909 Journal homepage: http://www.ijcmas.com Ganoderma lucidum is considered as one of the richest sources of natural antibiotics and various species of them inhibit the growth of a wide diversity of micro organisms. The pharmacological activities of Ganoderma lucidum, especially its intrinsic immunomodulating and antitumor properties have been w...

Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease.

Two new lanostane-type triterpenes, lucidumol A and ganoderic acid beta, were isolated from the spores of Ganoderma (G.) lucidum, together with a new natural one and seven that were known. The structures of the new triterpenes were determined as (24S)-24,25-dihydroxylanost-8-ene-3,7-dione and 3 beta,7 beta-dihydroxy-11,15-dioxolanosta-8,24(E)-dien-26-oic acid, respectively, by chemical and spec...

Ganoderma lucidum

Effect of Ganoderma Lucidum on Cytokine Release by Peritoneal Macrophages

Background: The water-soluble extract of Ganoderma lucidum (Reishi) has been used as an immunomodulator to stimulate spleen cells proliferation and cytokine expression. Objective: To investigate the effect of Ganoderma lucidum (G. lucidum) on cytokine production by mice peritoneal macrophages. Methods: Mice peritoneal macrophages were prepared by intra-peritoneal injection of 5 ml cold PBS. Per...

Inhibitory effect of methanol extract of Ganoderma lucidum on acute itch-associated responses in mice.

In this study, the antipruritic effect of the methanol extract of Ganoderma lucidum (MEGL) was studied in mice. Oral administration of MEGL (10-1000 mg/kg) produced a dose-dependent inhibition of scratching, an itch-related response, induced by intradermal 5-hydroxytryptamine (5-HT) (100 nmol/site), alpha-methyl-5-HT (100 nmol/site), and proteinase-activated receptor-2 (PAR(2))-activating pepti...